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    1. 主营产品: 科研人类ELISA试剂盒说明书,大鼠ELISA试剂盒代测,小鼠ELISA试剂盒厂家
      产品分类

      公司名称:上海古朵生物科技有限公司

      公司地址:上海市嘉定区曹安公路5588号

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      技术文章

      脱氧核糖核酸酶2抗体,DNase II应用方法

      发布时间:2022-05-16 阅读:103

      英文名称    DNase II    

      中文名称    脱氧核糖核酸酶2抗体    

      别    名    Acid DNase; Deoxyribonuclease 2 alpha; Deoxyribonuclease 2; Deoxyribonuclease II alpha; Deoxyribonuclease II; Deoxyribonuclease II lysosomal; Deoxyribonuclease-2-alpha; Deoxyribonuclease2; DeoxyribonucleaseII; DNASE 2; DNASE 2A; DNase II alpha; DNase II lysosomal; DNASE2; DNASE2A; DNaseII; DNL 2; DNL; DNL2; DNS2A_HUMAN; Lysosomal DNase II; R31240 2; R31240_2.    

      供 应 商    远慕生物

      研究领域    细胞生物  细胞凋亡  细胞周期蛋白  表观遗传学      

      抗体来源    Rabbit    

      克隆类型    Polyclonal    

      交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Sheep,     

      产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 脱氧核糖核酸酶2抗体(石蜡切片需做抗原修复) 
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.    

      分 子 量    38kDa    

      细胞定位    细胞浆     

      性    状    Lyophilized or Liquid    

      浓    度    1mg/1ml    

      免 疫 原    KLH conjugated synthetic peptide derived from human DNase II    

      亚    型    IgG    

      纯化方法    affinity purified by Protein A    

      储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

      保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

      脱氧核糖核酸酶2抗体产品介绍    background:

      Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

      Function:
      Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

      Subcellular Location:
      Lysosome. 

      Post-translational modifications:
      Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.

      Similarity:
      Belongs to the DNase II family.

      Database links:
      UniProtKB/Swiss-Prot: O00115.2

      important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

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